Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566734 | 1.00 | ADORA3 (0.53) | ADORA3RXFP1MAPTNPC1RAB9A | |
| SCHEMBL8572901 | 0.92 | ADORA3 (0.55) | ADORA3RXFP1MAPTNPC1RAB9A | |
| SCHEMBL8572906 | 0.92 | ADORA3 (0.55) | ADORA3RXFP1MAPTNPC1RAB9A | |
| SCHEMBL8571932 | 0.82 | MAPT (0.40) | ADORA3MAPTNPC1RAB9APKM | |
| SCHEMBL8571928 | 0.82 | MAPT (0.40) | ADORA3MAPTNPC1RAB9APKM | |
| SCHEMBL30911334 | 0.82 | ADORA3 (0.61) | ADORA3RXFP1MAPTNPC1RAB9A | |
| SCHEMBL8567225 | 0.81 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2CYP2C9NPSR1 | |
| SCHEMBL8567222 | 0.81 | SMN1; SMN2 (0.48) | NPC1RAB9ASMN1; SMN2CYP2C9NPSR1 | |
| SCHEMBL8573144 | 0.80 | ADORA3 (0.62) | ADORA3RXFP1MAPTNPC1RAB9A | |
| SCHEMBL8988413 | 0.80 | LMNA (0.38) | ADORA3RXFP1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |