Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | PCNA | P12004 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316261 | 0.85 | MTNR1A (0.61) | MTNR1AHSD17B1HSD17B2POLBMMP2 | |
| SCHEMBL8569927 | 0.84 | MEN1 (0.49) | MTNR1AMEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL63388 | 0.84 | KMT2A (0.55) | MTNR1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL25648716 | 0.83 | POLB (0.71) | MEN1KMT2AALDH1A1HPGDAPOBEC3A | |
| SCHEMBL24483184 | 0.78 | KMT2A (0.62) | MTNR1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7199212 | 0.78 | KMT2A (0.58) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL8017020 | 0.76 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL12228278 | 0.76 | F2RL1 (0.69) | MEN1KMT2AHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL24202101 | 0.76 | HTR2A (0.55) | MTNR1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12226957 | 0.75 | CYP2D6 (0.53) | MEN1KMT2AALDH1A1HPGDAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |