Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566735 | 0.84 | MTNR1A (0.61) | MEN1KMT2AMTNR1AALDH1A1HPGD | |
| SCHEMBL4364311 | 0.84 | POLB (0.60) | MEN1KMT2AMTNR1AALDH1A1HPGD | |
| SCHEMBL4362583 | 0.84 | MEN1 (0.64) | MEN1KMT2AALDH1A1HSD17B10APLNR | |
| SCHEMBL3918324 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1HPGDAPOBEC3A | |
| SCHEMBL4708186 | 0.83 | MEN1 (0.51) | MEN1KMT2AMTNR1AALDH1A1HTT | |
| SCHEMBL1922374 | 0.81 | CYP3A4 (0.49) | MEN1KMT2AALDH1A1HPGDAPOBEC3A | |
| SCHEMBL4664847 | 0.81 | HSD17B10 (0.65) | MEN1KMT2AHTTHSD17B10 | |
| SCHEMBL6995409 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDAPOBEC3A | |
| SCHEMBL7961893 | 0.81 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDAPOBEC3A | |
| SCHEMBL6994008 | 0.81 | SMN1; SMN2 (0.50) | MEN1KMT2AALDH1A1HPGDAPOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |