Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561817 | 0.83 | HPGD (0.42) | ALDH1A1HSD17B10BCHEHPGDHTT | |
| SCHEMBL8561825 | 0.83 | HPGD (0.42) | ALDH1A1HSD17B10BCHEHPGDHTT | |
| SCHEMBL8561821 | 0.83 | HPGD (0.42) | ALDH1A1HSD17B10BCHEHPGDHTT | |
| SCHEMBL8562883 | 0.79 | HSD17B10 (0.38) | ALDH1A1HSD17B10HPGDHTTGAA | |
| SCHEMBL8444707 | 0.79 | HSD17B10 (0.44) | ALDH1A1HSD17B10BCHECYP3A4HTT | |
| SCHEMBL8562879 | 0.79 | HSD17B10 (0.38) | ALDH1A1HSD17B10HPGDHTTGAA | |
| SCHEMBL8565239 | 0.79 | HSD17B10 (0.38) | ALDH1A1HSD17B10HPGDHTTGAA | |
| SCHEMBL8567220 | 0.79 | HSD17B10 (0.44) | ALDH1A1HSD17B10BCHECYP3A4HTT | |
| SCHEMBL8567223 | 0.79 | HSD17B10 (0.44) | ALDH1A1HSD17B10BCHECYP3A4HTT | |
| SCHEMBL8571137 | 0.73 | HPGD (0.76) | ALDH1A1HSD17B10HPGDCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |