Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566832 | 1.00 | HSD17B10 (0.44) | HSD17B10MAPTRAB9ASMN1; SMN2RECQL | |
| SCHEMBL9241968 | 0.73 | RECQL (0.42) | HSD17B10MAPTRAB9ASMN1; SMN2RECQL | |
| SCHEMBL9241954 | 0.73 | RECQL (0.42) | HSD17B10MAPTRAB9ASMN1; SMN2RECQL | |
| Hydroxyamine SCHEMBL7465841 | 0.73 | RAB9A (0.41) | HSD17B10MAPTRAB9ASMN1; SMN2RECQL | |
| SCHEMBL10670216 | 0.68 | RECQL (0.48) | HSD17B10MAPTRAB9ASMN1; SMN2RECQL | |
| SCHEMBL10844670 | 0.67 | RECQL (0.44) | HSD17B10MAPTRAB9ASMN1; SMN2RECQL | |
| SCHEMBL5962443 | 0.65 | ALDH1A1 (0.54) | HSD17B10MAPTRAB9ASMN1; SMN2RECQL | |
| SCHEMBL28703842 | 0.65 | SLC7A5 (0.54) | SLC7A5 | |
| SCHEMBL8564937 | 0.65 | GRM2 (0.39) | HSD17B10SLC7A5 | |
| SCHEMBL8564931 | 0.65 | GRM2 (0.39) | HSD17B10SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |