Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8688742 | 0.98 | PGK1 (0.41) | PGK1LMNAHPGDTSHRMAPT | |
| SCHEMBL6736264 | 0.86 | PGK1 (0.41) | PGK1LMNAHPGDTSHRMAPT | |
| Hydrochloric Acid SCHEMBL6831309 | 0.85 | PGK1 (0.40) | PGK1LMNAHPGDTSHRMAPT | |
| SCHEMBL1477394 | 0.76 | TSHR (0.54) | PGK1LMNAHPGDTSHRMAPT | |
| SCHEMBL16774467 | 0.75 | HDAC6 (0.45) | PGK1MAPTHDAC1HDAC2HDAC8 | |
| SCHEMBL1477058 | 0.73 | LMNA (0.44) | PGK1LMNAHPGDTSHRMAPT | |
| SCHEMBL10977285 | 0.73 | LMNA (0.48) | PGK1LMNAHPGDTSHRHDAC8 | |
| SCHEMBL8878096 | 0.73 | SYK (0.49) | PGK1LMNAHPGDTSHRMAPT | |
| SCHEMBL10984450 | 0.73 | GRM4 (0.47) | MAPTHDAC6MAOAGRM4MAOB | |
| SCHEMBL16774344 | 0.72 | PGK1 (0.53) | PGK1LMNAHPGDTSHRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690860-B1 | HERBICIDAL TRIAZOLINONES | DU PONT (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5728651-A | Herbicidal triazolinones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0690860-A1 | HERBICIDAL TRIAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022860-A1 | HERBICIDAL TRIAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-13 | — | — | WO | disclosed |