Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970899 | 0.92 | L3MBTL1 (0.36) | L3MBTL1GPR119MAPK1TSHRLMNA | |
| SCHEMBL6970169 | 0.92 | L3MBTL1 (0.36) | L3MBTL1GPR119MAPK1TSHRLMNA | |
| SCHEMBL6968586 | 0.92 | L3MBTL1 (0.36) | L3MBTL1GPR119MAPK1TSHRLMNA | |
| SCHEMBL6965750 | 0.90 | ERN1 (0.35) | L3MBTL1GPR119MAPK1LMNARAB9A | |
| SCHEMBL8567886 | 0.85 | L3MBTL1 (0.54) | L3MBTL1MAPK1TSHRCHRM1NPSR1 | |
| SCHEMBL6956392 | 0.84 | CHRM1 (0.34) | GPR119MAPK1LMNARAB9AERN1 | |
| SCHEMBL12306394 | 0.79 | L3MBTL1 (0.38) | L3MBTL1GPR119MAPK1TSHRLMNA | |
| SCHEMBL29249360 | 0.79 | L3MBTL1 (0.35) | L3MBTL1GPR119MAPK1TSHRLMNA | |
| Bromide SCHEMBL8560104 | 0.77 | L3MBTL1 (0.42) | L3MBTL1GPR119MAPK1TSHRLMNA | |
| Bromide SCHEMBL8899531 | 0.77 | L3MBTL1 (0.42) | L3MBTL1GPR119MAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| CN-1150950-A | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1997-06-04 | — | — | CN | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |