Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888867 | 1.00 | FOLH1 (0.47) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL1889778 | 0.94 | DPP8 (0.47) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL1649812 | 0.91 | FOLH1 (0.48) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL7751944 | 0.89 | DPP7 (0.50) | GSRDPP8DPP9DPP7DPP4 | |
| SCHEMBL7751947 | 0.89 | DPP7 (0.50) | GSRDPP8DPP9DPP7DPP4 | |
| SCHEMBL2192330 | 0.88 | DPP8 (0.45) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL9142314 | 0.88 | DPP4 (0.54) | FOLH1GSRDPP8DPP9DPP4 | |
| SCHEMBL2196575 | 0.86 | FOLH1 (0.41) | FOLH1GSRDPP8DPP9DPP7 | |
| SCHEMBL2193972 | 0.85 | FOLH1 (0.43) | FOLH1DPP8DPP9DPP7DPP4 | |
| SCHEMBL2181866 | 0.84 | TERT (0.43) | FOLH1GSRDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819135-A1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031532-A1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-10 | — | — | WO | disclosed |