Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 6/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193972 | 0.93 | FOLH1 (0.43) | FOLH1BMP1BACE1CTSDGRIN2D | |
| SCHEMBL2202327 | 0.93 | FOLH1 (0.43) | FOLH1BMP1BACE1CTSDGRIN2D | |
| SCHEMBL2183342 | 0.92 | FOLH1 (0.44) | FOLH1BMP1BACE1CTSDGRIN2D | |
| SCHEMBL2182643 | 0.87 | BMP1 (0.45) | FOLH1BMP1BACE1CTSDDPP8 | |
| SCHEMBL1649812 | 0.87 | FOLH1 (0.48) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2195713 | 0.87 | DPP4 (0.43) | BMP1BACE1CTSDDPP8DPP9 | |
| SCHEMBL2194678 | 0.87 | BMP1 (0.44) | FOLH1BMP1BACE1CTSDGRIN2D | |
| SCHEMBL1888867 | 0.86 | FOLH1 (0.47) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8567236 | 0.86 | FOLH1 (0.47) | FOLH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2192330 | 0.86 | DPP8 (0.45) | FOLH1DPP8DPP9DPP7GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680263-B2 | Carbohydrate-based drug delivery polymers and conjugates thereof | NEKTAR THERAPEUTICS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | STT3B, STT3A, DDOST | FOLH1 287/4885BMP1 2155/4885BACE1 3429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.