Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.56 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568419 | 0.78 | KMT2A (0.41) | FSCN1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL6962533 | 0.76 | FSCN1 (0.50) | FSCN1TSPORAB9ANPC1HTT | |
| SCHEMBL17513418 | 0.76 | FSCN1 (0.53) | FSCN1TSPORAB9AALDH1A1POLB | |
| SCHEMBL13310151 | 0.74 | FSCN1 (0.71) | FSCN1TSPOSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL20708217 | 0.74 | FSCN1 (0.56) | FSCN1TSPOSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL6393802 | 0.71 | FSCN1 (0.61) | FSCN1TSPOSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL24534986 | 0.70 | FSCN1 (0.47) | FSCN1TSPOSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL11219137 | 0.70 | FSCN1 (0.36) | FSCN1SLC6A4ALDH1A1POLBMEN1 | |
| SCHEMBL7748464 | 0.70 | LMNA (0.45) | RAB9AALDH1A1NPC1POLBMEN1 | |
| SCHEMBL4015170 | 0.69 | FSCN1 (0.54) | FSCN1TSPOSLC6A4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |