Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361704 | 0.82 | BDKRB2 (0.40) | KMT2AMEN1ALDH1A1KDM4EBDKRB2 | |
| SCHEMBL8567564 | 0.78 | FSCN1 (0.56) | KMT2AMEN1ALDH1A1RAB9AFSCN1 | |
| SCHEMBL8563210 | 0.70 | USP2 (0.63) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL7748464 | 0.69 | LMNA (0.45) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL348700 | 0.69 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8568846 | 0.67 | KMT2A (0.63) | KMT2AMEN1ALDH1A1KDM4ERAB9A | |
| SCHEMBL6975522 | 0.65 | BDKRB2 (0.50) | BDKRB2 | |
| SCHEMBL2321618 | 0.65 | ALDH1A1 (0.35) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL15814152 | 0.63 | CA12 (0.53) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8477264 | 0.63 | GABRP (0.47) | BDKRB2FSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |