Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8599463 | 0.90 | MEN1 (0.43) | NTRK1NAMPTCYP3A4HTTL3MBTL1 | |
| SCHEMBL8602351 | 0.88 | TYK2 (0.48) | TYK2TP53NAMPTJAK2JAK1 | |
| SCHEMBL8597110 | 0.88 | LMNA (0.43) | TP53CYP3A4L3MBTL1KMT2ATRPV1 | |
| Hydrochloric Acid SCHEMBL8596734 | 0.88 | TYK2 (0.52) | TYK2TP53JAK2JAK1CYP3A4 | |
| SCHEMBL8596981 | 0.86 | TP53 (0.44) | TYK2TP53HTTL3MBTL1ALDH1A1 | |
| SCHEMBL8598838 | 0.85 | TP53 (0.43) | TYK2TP53HTTL3MBTL1ALDH1A1 | |
| SCHEMBL8597757 | 0.85 | L3MBTL1 (0.46) | TYK2TP53HTTL3MBTL1ALDH1A1 | |
| SCHEMBL8603765 | 0.85 | TYK2 (0.46) | TYK2TP53JAK2JAK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8597961 | 0.85 | POLB (0.50) | NTRK1KMT2ASMN1; SMN2 | |
| SCHEMBL8600758 | 0.85 | HPGD (0.46) | TP53HTTL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |