Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | MGMT | P16455 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601327 | 0.82 | MAPT (0.45) | ALDH1A1MAPTKDM4ERAB9AGAA | |
| SCHEMBL8567818 | 0.81 | HPGD (0.40) | KMT2AMAPTKDM4EMGMTRAB9A | |
| SCHEMBL8563794 | 0.81 | MGMT (0.50) | ALDH1A1KMT2AMAPTKDM4EMAOB | |
| SCHEMBL8563341 | 0.81 | MAPT (0.49) | ALDH1A1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL8560819 | 0.80 | HPGD (0.53) | MAPTKDM4EADORA2AGAAHPGD | |
| SCHEMBL8561968 | 0.79 | MAP2K3 (0.49) | ALDH1A1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL8563863 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTKDM4EMAOB | |
| SCHEMBL8565819 | 0.78 | HSD17B10 (0.49) | ALDH1A1KMT2AMAPTKDM4ERAB9A | |
| SCHEMBL8567714 | 0.78 | MGMT (0.61) | MGMTLMNAL3MBTL1THRB | |
| SCHEMBL19936505 | 0.76 | TDP1 (0.59) | ALDH1A1KMT2AMAPTKDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |