Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 9/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311200 | 0.90 | MGMT (0.64) | MGMTLMNAPIN1PDE5AL3MBTL1 | |
| SCHEMBL311607 | 0.83 | MGMT (0.59) | MGMTLMNAPIN1PDE5AL3MBTL1 | |
| SCHEMBL8563177 | 0.82 | TSHR (0.48) | MGMTLMNA | |
| SCHEMBL311450 | 0.82 | MGMT (0.57) | MGMTLMNAPIN1PDE5AL3MBTL1 | |
| SCHEMBL8600045 | 0.81 | TLR8 (0.42) | MGMTLMNAL3MBTL1CNR1ACHE | |
| SCHEMBL311056 | 0.80 | MGMT (0.59) | MGMTLMNAPIN1L3MBTL1THRB | |
| SCHEMBL1232862 | 0.80 | L3MBTL1 (0.57) | MGMTLMNAPIN1PDE5AL3MBTL1 | |
| SCHEMBL8566311 | 0.79 | MGMT (0.61) | MGMTLMNAPIN1ELANE | |
| SCHEMBL8565786 | 0.78 | SMN1; SMN2 (0.39) | MGMTLMNAACHE | |
| SCHEMBL8568326 | 0.78 | MGMT (0.44) | MGMTLMNAPIN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |