Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MGMT | P16455 | 2/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600045 | 0.86 | TLR8 (0.42) | MGMTNCF1LMNAALDH1A1TOP2A | |
| SCHEMBL8567714 | 0.82 | MGMT (0.61) | MGMTLMNA | |
| SCHEMBL8566973 | 0.81 | POLB (0.43) | TSHRPOLBMGMTEGFRNCF1 | |
| SCHEMBL8562740 | 0.80 | MGMT (0.43) | TSHRPOLBMGMTEGFRNCF1 | |
| SCHEMBL8561287 | 0.78 | POLB (0.42) | TSHRPOLBNCF1ALDH1A1MPO | |
| SCHEMBL8565786 | 0.76 | SMN1; SMN2 (0.39) | TSHRPOLBMGMTEGFRLMNA | |
| SCHEMBL8566327 | 0.75 | MGMT (0.38) | TSHRPOLBMGMTEGFRLMNA | |
| SCHEMBL8564067 | 0.75 | EGFR (0.39) | TSHRPOLBMGMTEGFRNCF1 | |
| SCHEMBL8564063 | 0.75 | EGFR (0.39) | TSHRPOLBMGMTEGFRNCF1 | |
| SCHEMBL8564398 | 0.73 | POLB (0.43) | POLBMGMTEGFRNCF1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |