Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29871162 | 0.80 | MEN1 (0.54) | MAPTSMN1; SMN2HTTKDM4EMITF | |
| SCHEMBL14764478 | 0.80 | MEN1 (0.54) | MAPTSMN1; SMN2HTTKDM4EMITF | |
| SCHEMBL8560413 | 0.78 | KMT2A (0.33) | MAPTSMN1; SMN2HTTKDM4ELMNA | |
| SCHEMBL8562469 | 0.78 | MAPT (0.41) | MAPTSMN1; SMN2HTTKDM4EMITF | |
| SCHEMBL8564101 | 0.75 | MGMT (0.38) | MAPTSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL1877935 | 0.74 | NOS3 (0.42) | MAPTSMN1; SMN2 | |
| SCHEMBL9909759 | 0.74 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2HTTKDM4EMITF | |
| SCHEMBL4462548 | 0.74 | MAPT (0.48) | MAPTSMN1; SMN2HTTKDM4EMITF | |
| SCHEMBL11708343 | 0.73 | MAPT (0.47) | MAPTSMN1; SMN2HTTKDM4EMITF | |
| SCHEMBL16919107 | 0.73 | MAPT (0.45) | MAPTSMN1; SMN2HTTKDM4EMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |