Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567775 | 0.78 | MAPT (0.41) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL8568195 | 0.78 | KMT2A (0.36) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL8563924 | 0.78 | KMT2A (0.50) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL1877935 | 0.74 | NOS3 (0.42) | MAPTRAB9ANPC1SMN1; SMN2BACE1 | |
| SCHEMBL8563136 | 0.73 | IKBKB (0.45) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL8562204 | 0.72 | S1PR4 (0.38) | MAPTLMNAS1PR4ROCK1KDM4E | |
| SCHEMBL8141010 | 0.72 | HTT (0.37) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL8564951 | 0.72 | ALDH1A1 (0.34) | KMT2AMEN1MAPTRAB9ALMNA | |
| SCHEMBL8601222 | 0.72 | MAPT (0.42) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL8566190 | 0.72 | KMT2A (0.58) | KMT2AMEN1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |