Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536319 | 0.89 | CYP4F2 (0.55) | CYP4F2CYP4A11PTPN1CYP1A2CYP3A4 | |
| SCHEMBL21439302 | 0.86 | PKM (0.49) | SMN1; SMN2POLBALDH1A1ALOX5 | |
| Hexane SCHEMBL21545246 | 0.81 | NR4A1 (0.48) | SMN1; SMN2POLBALDH1A1 | |
| Hexane SCHEMBL31090093 | 0.81 | NR4A1 (0.48) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL434221 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11 | |
| SCHEMBL1246063 | 0.81 | CYP4F2 (0.76) | CYP4F2CYP4A11PTPN1CYP1A2CYP3A4 | |
| SCHEMBL18670035 | 0.80 | CYP4F2 (0.48) | CYP4F2CYP4A11PTPN1CYP3A4CYP2C9 | |
| SCHEMBL2428470 | 0.80 | CYP4F2 (0.57) | CYP4F2CYP4A11PTPN1ALDH1A1 | |
| SCHEMBL2772418 | 0.79 | CYP4F2 (0.68) | CYP4F2CYP4A11PTPN1ALOX5 | |
| SCHEMBL10635313 | 0.79 | CYP4F2 (0.53) | CYP4F2CYP4A11POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0743064-A1 | Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease | ELI LILLY AND COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5462954-A | Antiinflammatory, antiallergens; treating asthma | ELI LILLY AND COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |