Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566037 | 0.87 | FAAH (0.42) | FAAHCNR2CNR1S1PR1HIF1A | |
| SCHEMBL8570953 | 0.87 | RARA (0.39) | FAAHCNR2CNR1S1PR1HIF1A | |
| SCHEMBL8615102 | 0.87 | RARA (0.48) | FAAHCNR2CNR1S1PR1MEN1 | |
| SCHEMBL8567722 | 0.87 | RARA (0.51) | FAAHCNR2S1PR1HIF1AEPAS1 | |
| SCHEMBL8570613 | 0.86 | RARA (0.38) | FAAHCNR2CNR1S1PR1HIF1A | |
| SCHEMBL8568931 | 0.86 | RARA (0.40) | FAAHCNR2CNR1S1PR1HIF1A | |
| SCHEMBL8566864 | 0.85 | CNR2 (0.47) | FAAHCNR2CNR1MEN1KMT2A | |
| SCHEMBL8566699 | 0.85 | RARB (0.56) | FAAHCNR2CNR1S1PR1HIF1A | |
| SCHEMBL8570419 | 0.85 | RARA (0.44) | FAAHCNR2CNR1S1PR1HIF1A | |
| SCHEMBL8567783 | 0.85 | CNR2 (0.47) | FAAHCNR2CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |