Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569669 | 0.89 | F2 (0.43) | ALDH1A1MAPTRAB9ANPSR1F2 | |
| SCHEMBL8569756 | 0.87 | F2 (0.40) | ALDH1A1MAPTRAB9ANPSR1NPC1 | |
| SCHEMBL8569675 | 0.86 | F2 (0.42) | ALDH1A1MAPTRAB9ANPSR1F2 | |
| SCHEMBL20565357 | 0.84 | KMT2A (0.44) | ALDH1A1MAPTRAB9ANPSR1NPC1 | |
| SCHEMBL8569502 | 0.81 | F2 (0.39) | ALDH1A1MAPTRAB9ANPSR1F2 | |
| SCHEMBL26325186 | 0.77 | KMT2A (0.46) | ALDH1A1MAPTRAB9ANPSR1NPC1 | |
| SCHEMBL8572820 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9ANPSR1F2 | |
| SCHEMBL6024561 | 0.76 | KMT2A (0.51) | ALDH1A1MAPTRAB9ANPSR1NPC1 | |
| SCHEMBL26327363 | 0.76 | KMT2A (0.39) | ALDH1A1MAPTRAB9ANPSR1NPC1 | |
| SCHEMBL6024564 | 0.76 | KMT2A (0.51) | ALDH1A1MAPTRAB9ANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773624-A | Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0795551-A1 | Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1997-09-17 | — | — | EP | disclosed |