Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569756 | 0.89 | F2 (0.40) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8572820 | 0.89 | ALDH1A1 (0.41) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8569669 | 0.89 | F2 (0.43) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8567963 | 0.81 | ALDH1A1 (0.38) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL26324757 | 0.79 | F2 (0.44) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8569675 | 0.79 | F2 (0.42) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL26325189 | 0.73 | KMT2A (0.43) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL13673554 | 0.70 | F2 (0.55) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8569933 | 0.70 | ALDH1A1 (0.41) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL22980477 | 0.69 | F2 (0.49) | F2PRSS1PRSS2PRSS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773624-A | Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0795551-A1 | Method for preparing 5-amino-1,2,4-thiadiazol acetic acid derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1997-09-17 | — | — | EP | disclosed |