Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.61 |
| ▸ | VDR | P11473 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568004 | 1.00 | GPBAR1 (0.61) | GPBAR1VDRHIF1ACYP2C9EPHA2 | |
| SCHEMBL1133762 | 0.91 | GPBAR1 (0.58) | GPBAR1VDRHIF1ACYP2C9EPHA2 | |
| SCHEMBL1133763 | 0.91 | GPBAR1 (0.58) | GPBAR1VDRHIF1ACYP2C9EPHA2 | |
| SCHEMBL5577551 | 0.87 | GPBAR1 (0.73) | GPBAR1VDRHIF1AEPHA2CASP7 | |
| SCHEMBL11525625 | 0.87 | GPBAR1 (0.62) | GPBAR1VDRHIF1ACYP2C9EPHA2 | |
| SCHEMBL11525628 | 0.87 | GPBAR1 (0.62) | GPBAR1VDRHIF1ACYP2C9EPHA2 | |
| SCHEMBL5577556 | 0.87 | GPBAR1 (0.73) | GPBAR1VDRHIF1AEPHA2CASP7 | |
| SCHEMBL18575950 | 0.86 | GPBAR1 (0.80) | GPBAR1VDRHIF1ACYP2C9EPHA2 | |
| SCHEMBL22871996 | 0.86 | GPBAR1 (0.80) | GPBAR1VDRHIF1ACYP2C9EPHA2 | |
| SCHEMBL22871867 | 0.86 | GPBAR1 (0.80) | GPBAR1VDRHIF1ACYP2C9EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786131-A | COATING SUBSTRATE WITH FILM COMPRISING RADIATION SENSITIVE ACID GENERATOR, ANDROSTANE-17-ALKYLCARBOXYLATE, AND ACRYLIC POLYMER, EXPOSING, DEVELOPING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1998-07-28 | — | — | US | claimed |
| EP-0690348-A2 | Photoresist composition for deep ultraviolet radiation and process for its use | International Business Machines Corporation (US) | 1996-01-03 | — | — | EP | claimed |