Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179284 | 0.80 | CYP19A1 (0.42) | CYP19A1KDM4EHSP90AA1POLBNAPRT | |
| SCHEMBL31256061 | 0.80 | CYP19A1 (0.42) | CYP19A1KDM4EHSP90AA1POLBNAPRT | |
| SCHEMBL21169011 | 0.79 | CYP19A1 (0.36) | CYP19A1KDM4EHSP90AA1NPC1RAB9A | |
| SCHEMBL11125408 | 0.79 | CYP19A1 (0.36) | CYP19A1KDM4EHSP90AA1SMN1; SMN2 | |
| SCHEMBL19522790 | 0.79 | CYP19A1 (0.36) | CYP19A1KDM4EHSP90AA1POLBNPC1 | |
| SCHEMBL21308429 | 0.77 | SMN1; SMN2 (0.45) | CYP19A1KDM4EPOLBNPC1RAB9A | |
| SCHEMBL20774860 | 0.76 | CYP19A1 (0.40) | CYP19A1KDM4EHSP90AA1POLBNAPRT | |
| SCHEMBL8289716 | 0.76 | CYP19A1 (0.40) | CYP19A1KDM4EHSP90AA1POLBNAPRT | |
| SCHEMBL9589700 | 0.76 | CYP19A1 (0.40) | CYP19A1KDM4EHSP90AA1POLBNAPRT | |
| SCHEMBL19573760 | 0.76 | HSP90AA1 (0.42) | CYP19A1KDM4EHSP90AA1POLBNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455533-B1 | Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives | ATOCHEM (FR) | 1993-12-15 | — | — | EP | claimed |
| US-5169980-A | Catalytic reaction of benzyl chloride and alkali metal methacrylate | ELF ATOCHEM S.A. (FR) | 1992-12-08 | — | — | US | claimed |
| EP-0455533-A1 | Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives | ELF ATOCHEM S.A. (FR) | 1991-11-06 | — | — | EP | claimed |
| JP-5043513-A | — | — | None | — | — | JP | disclosed |
| CN-116675727-A | Method for synthesizing amide and/or polypeptide by taking unprotected amino acid as ammonia component | 广州医科大学 | 2023-09-01 | — | — | CN | disclosed |
| US-8247401-B2 | P2X3 receptor antagonists for treatment of pain | MERCK SHARP & DOHME CORP. (US) | 2012-08-21 | — | — | US | disclosed |
| US-8129389-B2 | Substituted oxindole derivatives, medicaments containing the latter and use thereof | ABBOTT GMBH & CO. KG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8129389-B2 | Substituted oxindole derivatives, medicaments containing the latter and use thereof | ABBOTT GMBH & CO. KG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20100266714-A1 | P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME LLC | 2010-10-21 | — | — | US | disclosed |
| US-20090186904-A1 | Substituted Oxindole Derivatives, Medicaments Containing the Latter and Use Thereof | ABBOTT GMBH & CO. KG | 2009-07-23 | — | — | US | disclosed |
| US-20090186904-A1 | Substituted Oxindole Derivatives, Medicaments Containing the Latter and Use Thereof | ABBOTT GMBH & CO. KG | 2009-07-23 | — | — | US | disclosed |
| EP-0455533-B1 | Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives | ATOCHEM (FR) | 1993-12-15 | — | — | EP | disclosed |
| JP-H0543513-A | NEW PRODUCTION METHOD OF BENZYL METHACRYLATE AND ITS DERIVATIVE WHICH ARE HALOGENATED OR ALKYLATED ON AROMATIC NUCLEUS | ELF ATOCHEM SA | 1993-02-23 | — | — | JP | disclosed |
| US-5169980-A | Catalytic reaction of benzyl chloride and alkali metal methacrylate | ELF ATOCHEM S.A. (FR) | 1992-12-08 | — | — | US | disclosed |
| EP-0455533-A1 | Process for the production of benzyl methacrylate and its aromatic ring substituted halogenated and alkylated derivatives | ELF ATOCHEM S.A. (FR) | 1991-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266714-A1 | P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | P2RX3, P2RX1, P2RX2 | CYP19A1 4780/4885KDM4E 4010/4885HSP90AA1 1637/4885 |
| US-20090186904-A1 | Substituted Oxindole Derivatives, Medicaments Containing the Latter and Use Thereof | OXTR, AVPR2, AVPR1B | CYP19A1 362/4885KDM4E 3956/4885HSP90AA1 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.