SCHEMBL8568173

SCHEMBL8568173

COc1cc(C(=O)O)ccc1Cn1c(C)nc2cnccc21.[NaH]

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.53
AGTR2 P50052 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8319621 0.89 AGTR1 (0.43) AGTR1AGTR2
SCHEMBL8567946 0.85 HDAC3 (0.57) AGTR1AGTR2
SCHEMBL8570880 0.80
SCHEMBL9272654 0.79 AGTR1 (0.55) AGTR1AGTR2
SCHEMBL7496365 0.79
SCHEMBL7501624 0.78
Hydrochloric Acid SCHEMBL8322173 0.78
SCHEMBL6170762 0.76 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL7493565 0.76 PTAFR (0.65)
SCHEMBL8324186 0.74 HDAC3 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0842175-A1 IMIDAZOPYRIDINE DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-05-20 EP disclosed
WO-1997006167-A1 IMIDAZOPYRIDINE DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-02-20 WO disclosed