Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | PTAFR | P25105 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324186 | 0.88 | HDAC3 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8568173 | 0.85 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8570880 | 0.82 | — | — | |
| SCHEMBL7496365 | 0.80 | — | — | |
| SCHEMBL7501624 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL8322173 | 0.79 | — | — | |
| SCHEMBL6170405 | 0.75 | HDAC1 (0.59) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7496109 | 0.75 | PTAFR (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7501906 | 0.75 | PTAFR (0.80) | PTAFR | |
| SCHEMBL7497573 | 0.74 | PTAFR (0.78) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842175-A1 | IMIDAZOPYRIDINE DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006167-A1 | IMIDAZOPYRIDINE DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-02-20 | — | — | WO | disclosed |