Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634009 | 0.82 | PDE4A (0.42) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL8571350 | 0.82 | ANPEP (0.34) | CTSSCTSKPDE4A | |
| SCHEMBL8629599 | 0.80 | PDE4A (0.44) | ALDH1A1TSHRPDE4APDE4BPDE4C | |
| SCHEMBL1553442 | 0.79 | ALOX5AP (0.45) | ALOX5APSLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL1554521 | 0.79 | ALOX5AP (0.39) | ALOX5APSLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL8572847 | 0.78 | PTGDR2 (0.41) | ALOX5APSLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL8574221 | 0.78 | TNKS (0.42) | HPGD | |
| Hydrochloric Acid SCHEMBL8605074 | 0.78 | ALOX5AP (0.39) | ALOX5APSLC6A3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL8605067 | 0.77 | ALOX5AP (0.38) | ALOX5APSLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL8572616 | 0.76 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |