Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633509 | 0.87 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8571350 | 0.84 | ANPEP (0.34) | PDE4AMAOBADORA2A | |
| SCHEMBL8574221 | 0.82 | TNKS (0.42) | HPGDMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL8568221 | 0.82 | ALOX5AP (0.35) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8629585 | 0.82 | GAA (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8628572 | 0.81 | SMN1; SMN2 (0.39) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL8572616 | 0.81 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DMAOB | |
| SCHEMBL8629599 | 0.81 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2525079 | 0.80 | LMNA (0.36) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL8627255 | 0.80 | SMN1; SMN2 (0.41) | PDE4APDE4BPDE4CPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |