Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | SCN2B | O60939 | 2/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | DDT | P30046 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568280 | 1.00 | LMNA (0.42) | LMNAACACBSCN2BSCN1BSCN5A | |
| SCHEMBL8600287 | 0.92 | SCN2B (0.39) | LMNASCN2BSCN1BSCN5ASCN9A | |
| SCHEMBL8600285 | 0.92 | SCN2B (0.39) | LMNASCN2BSCN1BSCN5ASCN9A | |
| SCHEMBL8566820 | 0.87 | NOTUM (0.40) | SCN2BSCN1BSCN5ASCN9AALDH1A1 | |
| SCHEMBL8566821 | 0.87 | NOTUM (0.40) | SCN2BSCN1BSCN5ASCN9AALDH1A1 | |
| SCHEMBL9064662 | 0.76 | LMNA (0.43) | LMNAACACBSCN2BSCN1BSCN5A | |
| SCHEMBL8570049 | 0.74 | HTT (0.41) | LMNAALDH1A1SMN1; SMN2BRD9HTT | |
| SCHEMBL8570767 | 0.72 | NOTUM (0.45) | SCN2BSCN1BSCN5ASCN9APOLB | |
| SCHEMBL8570769 | 0.72 | NOTUM (0.45) | SCN2BSCN1BSCN5ASCN9APOLB | |
| SCHEMBL9064664 | 0.68 | LMNA (0.43) | LMNAACACBALDH1A1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000408-A1 | N-PHENYLIMINO HETEROCYCLIC DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1998-01-08 | — | — | WO | disclosed |