Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599626 | 0.85 | HPGD (0.50) | KDM4EL3MBTL1MAPTPOLBHPGD | |
| SCHEMBL28460390 | 0.84 | EGFR (0.55) | KDM4EL3MBTL1MAPTPOLBHPGD | |
| SCHEMBL8562632 | 0.83 | L3MBTL1 (0.52) | KDM4EL3MBTL1POLBHPGDLMNA | |
| SCHEMBL8599924 | 0.83 | TLR7 (0.47) | KDM4EL3MBTL1MAPTPOLBHPGD | |
| SCHEMBL8564023 | 0.82 | MAPT (0.44) | KDM4EMAPTPOLBHPGDLMNA | |
| SCHEMBL8568375 | 0.82 | PDE10A (0.46) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8560819 | 0.81 | HPGD (0.53) | KDM4EL3MBTL1MAPTHPGDTACR3 | |
| SCHEMBL8559921 | 0.80 | IKBKB (0.42) | KDM4EL3MBTL1MAPTPOLBMAPK1 | |
| SCHEMBL8563794 | 0.80 | MGMT (0.50) | KDM4EMAPTPOLBHPGDLMNA | |
| SCHEMBL8568405 | 0.79 | HSD17B10 (0.52) | KDM4EMAPTPOLBHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |