Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568375 | 0.88 | PDE10A (0.46) | HSD17B10TP53PDE10AMAPTKMT2A | |
| SCHEMBL8559921 | 0.87 | IKBKB (0.42) | HSD17B10TP53PDE10AMAPTKMT2A | |
| SCHEMBL8567636 | 0.83 | HSD17B10 (0.56) | HSD17B10TP53PDE10AMAPTKMT2A | |
| SCHEMBL8564023 | 0.81 | MAPT (0.44) | MAPTKMT2AKDM4EMGMTLMNA | |
| SCHEMBL8562130 | 0.81 | MAPT (0.40) | HSD17B10TP53MAPTKMT2AKDM4E | |
| SCHEMBL8596872 | 0.80 | TLR8 (0.42) | HSD17B10MAPTKMT2AKDM4ELMNA | |
| SCHEMBL8567950 | 0.80 | CYP3A4 (0.47) | HSD17B10TP53MAPTKMT2AKDM4E | |
| SCHEMBL8568442 | 0.79 | KDM4E (0.52) | TP53MAPTKMT2AKDM4ELMNA | |
| SCHEMBL8567514 | 0.79 | S100A4 (0.54) | HSD17B10MAPTKMT2AKDM4EMGMT | |
| SCHEMBL8562456 | 0.79 | CYP3A4 (0.43) | HSD17B10MAPTKMT2AKDM4EMGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |