Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 8/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.52 |
| ▸ | REN | P00797 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996183 | 0.94 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL11787204 | 0.91 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL20148244 | 0.84 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL30433983 | 0.83 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL6882714 | 0.83 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL7951597 | 0.82 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL5668195 | 0.81 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL27580610 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL6719484 | 0.81 | REN (0.46) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL23529746 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |