Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563774 | 0.84 | MAPK1 (0.38) | ALDH1A1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL8563824 | 0.78 | MAPT (0.33) | MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL1515052 | 0.71 | NOS3 (0.32) | HSP90AA1HSP90AB1NOS3NOS2 | |
| SCHEMBL8133589 | 0.69 | L3MBTL1 (0.39) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL2586010 | 0.69 | L3MBTL1 (0.39) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL20526106 | 0.69 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL2186389 | 0.69 | NOS3 (0.33) | NOS3NOS2 | |
| SCHEMBL21268410 | 0.68 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL20526150 | 0.67 | NOS3 (0.32) | NOS3NOS2 | |
| SCHEMBL1787069 | 0.67 | PLAU (0.33) | ALDH1A1L3MBTL1ALOX15NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586393-B1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | claimed |
| US-5439910-A | For applying to plants, seeds or soils | ZENECA LIMITED (GB) | 1995-08-08 | — | — | US | claimed |