Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13166718 | 0.81 | SMN1; SMN2 (0.50) | MEN1KMT2ASMN1; SMN2KDM4ECNR1 | |
| SCHEMBL401068 | 0.80 | CNR1 (0.47) | MEN1KMT2AKDM4ECNR1CNR2 | |
| SCHEMBL29392762 | 0.80 | CNR1 (0.47) | MEN1KMT2AKDM4ECNR1CNR2 | |
| SCHEMBL249578 | 0.78 | NR4A1 (0.52) | KDM4ECNR1CNR2CXCR5ALDH1A1 | |
| SCHEMBL254968 | 0.78 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2KDM4EKEAP1 | |
| SCHEMBL27982028 | 0.77 | CYP2C9 (0.61) | MEN1KMT2ASMN1; SMN2CNR2MAPT | |
| SCHEMBL4031210 | 0.76 | ALDH1A1 (0.57) | MEN1KMT2ASMN1; SMN2CNR1CNR2 | |
| SCHEMBL2174146 | 0.76 | ATM (0.60) | KMT2AKDM4ECNR1CNR2CXCR5 | |
| SCHEMBL7970116 | 0.76 | GAA (0.61) | CNR1CNR2CXCR5GAAPDK2 | |
| SCHEMBL1096857 | 0.76 | BRD4 (0.50) | MEN1KMT2AKDM4ECXCR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |