Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580332 | 1.00 | MCL1 (0.67) | MCL1SLC9A1MAPTOPRM1OPRL1 | |
| SCHEMBL6368871 | 0.84 | MCL1 (0.59) | MCL1SLC9A1MAPTOPRM1OPRL1 | |
| SCHEMBL16599480 | 0.82 | MCL1 (0.76) | MCL1SLC9A1MAPTMEN1NPC1 | |
| SCHEMBL117186 | 0.80 | MCL1 (1.00) | MCL1SLC9A1MAPTMEN1NPC1 | |
| SCHEMBL401039 | 0.80 | MCL1 (0.73) | MCL1SLC9A1MAPTMEN1NPC1 | |
| SCHEMBL22022199 | 0.79 | RXFP1 (0.59) | MCL1MEN1KMT2AALDH1A1 | |
| SCHEMBL31435640 | 0.79 | MCL1 (0.69) | MCL1ALDH1A1 | |
| SCHEMBL29623497 | 0.79 | MCL1 (0.53) | MCL1ALDH1A1SYK | |
| SCHEMBL17102355 | 0.79 | MCL1 (0.53) | MCL1ALDH1A1SYK | |
| SCHEMBL2323444 | 0.79 | MCL1 (0.71) | MCL1SLC9A1MAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |