Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | ACLY | P53396 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43328 | 0.82 | KDM4E (0.66) | RXFP1MEN1KMT2AAHRPHGDH | |
| SCHEMBL17324809 | 0.82 | RXFP1 (0.64) | RXFP1MEN1KMT2AAHRPHGDH | |
| SCHEMBL31435640 | 0.81 | MCL1 (0.69) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL13415456 | 0.81 | RXFP1 (0.62) | RXFP1MEN1KMT2AAHRPHGDH | |
| SCHEMBL22003789 | 0.81 | ACLY (0.51) | RXFP1ACLYGFER | |
| SCHEMBL29580332 | 0.79 | MCL1 (0.67) | MEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL8568554 | 0.79 | MCL1 (0.67) | MEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL24198804 | 0.78 | RXFP1 (0.59) | RXFP1MEN1KMT2AAHRPHGDH | |
| SCHEMBL4919697 | 0.78 | L3MBTL1 (0.70) | RXFP1MEN1KMT2AAHRPHGDH | |
| SCHEMBL17321377 | 0.78 | RXFP1 (0.59) | RXFP1MEN1KMT2AAHRPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102616-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. (US) | 2020-05-22 | — | — | WO | disclosed |