SCHEMBL31435640

SCHEMBL31435640

CN(C)C(=O)c1cc2cc(Br)ccc2n1C

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.69
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29623497 0.88 MCL1 (0.53) MCL1ALDH1A1LMNA
SCHEMBL17102355 0.88 MCL1 (0.53) MCL1ALDH1A1LMNA
SCHEMBL22547022 0.85 MCL1 (0.62) MCL1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL16440985 0.82 MCL1 (0.76) MCL1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL418126 0.82 MCL1 (1.00) MCL1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL22022199 0.81 RXFP1 (0.59) MCL1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL3534182 0.81 MCL1 (0.73) MCL1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL8568554 0.79 MCL1 (0.67) MCL1ALDH1A1
SCHEMBL29580332 0.79 MCL1 (0.67) MCL1ALDH1A1
SCHEMBL1096760 0.78 L3MBTL1 (0.70) MCL1ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082069-A1 COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN 中国海洋大学 2025-04-24 WO disclosed
CN-119841843-A Compound combined with CRBN protein and degradation agent of CRBN protein 中国海洋大学 2025-04-18 CN disclosed