Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688848 | 0.82 | MAPT (0.47) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL9674605 | 0.82 | NOS3 (0.43) | MAPTKDM4ETSHRKMT2ATDP1 | |
| SCHEMBL18474448 | 0.78 | MAPT (0.45) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL783847 | 0.78 | HTT (0.45) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL29658100 | 0.78 | HTT (0.45) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL11708343 | 0.78 | MAPT (0.47) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL8565505 | 0.78 | MAPT (0.45) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL11713155 | 0.78 | MAPT (0.45) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL16919107 | 0.78 | MAPT (0.45) | MAPTHTTKDM4EMITFNOD2 | |
| SCHEMBL29674727 | 0.78 | NOS2 (0.50) | MAPTHTTKDM4EMITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |