SCHEMBL8568790

SCHEMBL8568790

COC(C)OCOc1ccc(C=O)c(C#Cc2ccccc2)c1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 2/20 0.31
RARA P10276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8566523 0.86 IKBKB (0.32) IKBKBRARA
SCHEMBL8568404 0.85 IKBKB (0.35) IKBKBRARA
SCHEMBL8575216 0.85 IKBKB (0.34) IKBKBRARA
SCHEMBL8574908 0.85 IKBKB (0.33) IKBKBRARA
SCHEMBL8570620 0.84 IKBKB (0.31) IKBKB
SCHEMBL8571821 0.82
SCHEMBL8691383 0.79 PTPN1 (0.41) IKBKBRARA
SCHEMBL8571818 0.77 RARA (0.36) IKBKBRARA
SCHEMBL8614548 0.75 RARA (0.42) IKBKBRARA
SCHEMBL8397842 0.74 MEN1 (0.31) IKBKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5798354-A COSMETIC, THERAPY CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) 1998-08-25 US claimed
US-5798354-A COSMETIC, THERAPY CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) 1998-08-25 US disclosed