Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537650 | 0.89 | MAPK1 (0.49) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1028660 | 0.85 | ESR1 (0.44) | MEN1KMT2AHSD17B10HSP90AA1ESR1 | |
| SCHEMBL29084824 | 0.85 | TTR (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL1027791 | 0.85 | CAMK2A (0.54) | CYP1A2CYP2C9CYP2C19HSD17B10PNLIP | |
| SCHEMBL18179765 | 0.81 | HSP90AA1 (0.47) | ALDH1A1HSD17B10HSP90AA1F2F10 | |
| SCHEMBL3781723 | 0.79 | TTR (0.65) | MAPTALDH1A1CYP2C9HPGDHSP90AA1 | |
| SCHEMBL20241705 | 0.79 | TSHR (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3469104 | 0.77 | TTR (0.61) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL989610 | 0.77 | MEN1 (0.74) | MEN1KMT2AMAPK1ESR1ESR2 | |
| SCHEMBL9657433 | 0.77 | MEN1 (0.74) | MEN1KMT2AMAPK1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857711-A1 | Process for the preparation of halogenated hydroxy diphenyl compounds | Ciba SC Holding AG (CH) | 1998-08-12 | — | — | EP | disclosed |