SCHEMBL989610

SCHEMBL989610

Oc1ccc(Oc2ccc(Cl)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.74
KMT2A Q03164 1/20 0.74
ESR1 P03372 1/20 0.74
ESR2 Q92731 1/20 0.74
LTA4H P09960 6/20 0.61
NR1H2 P55055 1/20 0.61
BAX Q07812 1/20 0.61
MAOA P21397 1/20 0.58
MAOB P27338 1/20 0.58
MAPK1 P28482 2/20 0.50
PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9657433 1.00 MEN1 (0.74) MEN1KMT2AESR1ESR2LTA4H
Methoxymethane SCHEMBL9362764 0.93 LTA4H (0.64) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL9503528 0.93 ESR2 (0.64) MEN1KMT2AESR1ESR2LTA4H
Diphenylether SCHEMBL9751425 0.88 LTA4H (0.74) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL249169 0.86 ESR2 (1.00) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL3175106 0.86 ESR2 (1.00) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL18198 0.86 ESR2 (1.00) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL457634 0.86 MAOA (0.74) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL7811939 0.86 ESR2 (1.00) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL9242729 0.86 MAOA (0.74) MEN1KMT2AESR1ESR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621175-B Difenoconazole hapten, artificial antigen, antibody and preparation method and application thereof 华南农业大学 2023-06-27 CN claimed
CN-114621175-A Difenoconazole hapten, artificial antigen, antibody and preparation method and application thereof 华南农业大学 2022-06-14 CN claimed
CN-106554382-B Application in nucleoside phosphoramidite class compound and preparation method thereof and drug 四川科伦博泰生物医药股份有限公司 2019-12-03 CN claimed
WO-2011011598-A1 PROCESS FOR PREPARING 4- { (S) -2- (4-(4-CHLOROPHENOXY) PHENOXYMETHYL) PYRROLIDIN-1-YL) } BUTYRIC ACID AND SALTS THEREOF DECODE GENETICS EHF (IS) 2011-01-27 WO claimed
EP-1664027-A1 SUBSTITUTED 2,3-DIHYDRO-1H-ISOINDOL-1-ONE DERIVATIVES AND METHODS OF USE AMGEN INC. (US) 2006-06-07 EP claimed
WO-2005021532-A1 SUBSTITUTED 2,3-DIHYDRO-1H-ISOINDOL-1-ONE DERIVATIVES AND METHODS OF USE AMGEN INC (US) 2005-03-10 WO claimed
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
US-20250197840-A1 ENGINEERED ENZYMES AND BIOPRODUCTION OF BAKUCHIOL INSCRIPTA, INC. 2025-06-19 US disclosed
US-12195775-B2 Engineered enzymes and bioproduction of bakuchiol INSCRIPTA, INC. (US) 2025-01-14 US disclosed
EP-4486905-A1 ENGINEERED ENZYMES AND BIOPRODUCTION OF BAKUCHIOL Inscripta, Inc. (US) 2025-01-08 EP disclosed
WO-2024119440-A1 BIODEGRADABLE MULTI-BLOCK COPOLYMERS COMPRISING LINKING UNITS DERIVED FROM CYCLIC KETENE ACETAL BASF SE (DE) 2024-06-13 WO disclosed
CN-118090684-A Reagent and method for rapid colorimetric fluorescence detection of mercury ions, iron ions, copper ions and zinc ions 石河子大学 2024-05-28 CN disclosed
US-20240101614-A1 CHAPERONES FOR HETEROLOGOUS EXPRESSION SYSTEMS INSCRIPTA, INC. (US) 2024-03-28 US disclosed
US-4156011-A TREATMENT OF CARDIOVASCULAR DISORDERS SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) 1979-05-22 US disclosed
US-4072754-A ANTICHOLESTEROL MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-02-07 US disclosed
US-4051173-A Phenoxyalkanol derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-09-27 US disclosed
US-4051170-A Diphenoxyacetic acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-09-27 US disclosed
US-3985875-A RENIN INHIBITION, ANTIHYPERTENSIVE, ANTICHOLESTEROL AGENTS DAINIPPON PHARMACEUTICAL CO., LTD. (JA) 1976-10-12 US disclosed
US-3954442-A 4-PHENOXY-PHENOXY-ALKANE-CARBOXYLIC ACIDS AND DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101614-A1 CHAPERONES FOR HETEROLOGOUS EXPRESSION SYSTEMS HSPA5, HSPA8, HSP90B1 MEN1 4460/4885KMT2A 3990/4885ESR1 3838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.