Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | STK39 | Q9UEW8 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179781 | 0.84 | HSD17B10 (0.41) | HSP90AA1HSD17B10CA12CA1CA2 | |
| SCHEMBL1027791 | 0.81 | CAMK2A (0.54) | HSD17B10CAMK2ATTRCYP3A4TSHR | |
| SCHEMBL8568945 | 0.81 | MEN1 (0.46) | HSP90AA1HSD17B10CA12CA1CA2 | |
| SCHEMBL22096454 | 0.79 | HSD17B10 (0.36) | HSP90AA1HSD17B10CA12CA1CA2 | |
| SCHEMBL1028660 | 0.78 | ESR1 (0.44) | HSP90AA1HSD17B10CAMK2AF2F10 | |
| SCHEMBL272067 | 0.76 | HSD17B10 (0.55) | HSP90AA1HSD17B10TTRALDH1A1CYP3A4 | |
| SCHEMBL10528411 | 0.74 | HSP90AA1 (0.57) | HSP90AA1HSD17B10TTRALDH1A1CYP3A4 | |
| SCHEMBL3159025 | 0.74 | KCNH2 (0.42) | HSP90AA1HSD17B10CA12CA2CA9 | |
| SCHEMBL10537650 | 0.73 | MAPK1 (0.49) | HSP90AA1HSD17B10TTRALDH1A1CYP3A4 | |
| SCHEMBL18179763 | 0.73 | HSP90AA1 (0.56) | HSP90AA1HSD17B10CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10684294-B2 | Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical | THE UNIVERSITY OF HONG KONG (HK) | 2020-06-16 | — | — | US | disclosed |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | VERSITECH LIMITED (HK) | 2016-10-27 | — | — | US | disclosed |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | VERSITECH LIMITED (HK) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | HAGH, HADH, FECH | HSP90AA1 1499/4885HSD17B10 332/4885CA12 1714/4885 |
| US-10684294-B2 | Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical | HAGH, HADH, FECH | HSP90AA1 1499/4885HSD17B10 332/4885CA12 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.