Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549765 | 0.79 | HTT (0.41) | KDM4EALDH1A1LMNAKCNH2UHRF1 | |
| Hydrochloric Acid SCHEMBL10858865 | 0.76 | UHRF1 (0.48) | KDM4ELMNATSHRUHRF1CCR1 | |
| Hydrochloric Acid SCHEMBL11412762 | 0.76 | UHRF1 (0.48) | KDM4ELMNATSHRUHRF1CCR1 | |
| SCHEMBL6641530 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1LMNAHPGDUHRF1 | |
| SCHEMBL15526300 | 0.74 | SLC22A12 (0.41) | KDM4EALDH1A1USP2LMNAMMP9 | |
| SCHEMBL29779666 | 0.73 | NOS2 (0.50) | KDM4EALDH1A1LMNATSHRHPGD | |
| SCHEMBL645891 | 0.73 | NOS2 (0.50) | KDM4EALDH1A1LMNATSHRHPGD | |
| SCHEMBL17643085 | 0.72 | TAAR1 (0.47) | KDM4EALDH1A1USP2LMNAMMP9 | |
| SCHEMBL5761353 | 0.72 | TAAR1 (0.47) | KDM4EALDH1A1USP2LMNAMMP9 | |
| SCHEMBL8565055 | 0.72 | UHRF1 (0.43) | KDM4EALDH1A1LMNATSHRUHRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |