Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RARA | P10276 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615102 | 0.90 | RARA (0.48) | FAAHCNR2S1PR1SMN1; SMN2MEN1 | |
| SCHEMBL9121371 | 0.89 | FAAH (0.49) | FAAHCNR2S1PR1SMN1; SMN2MEN1 | |
| SCHEMBL8567959 | 0.86 | FAAH (0.43) | FAAHCNR2S1PR1SMN1; SMN2MEN1 | |
| SCHEMBL8572221 | 0.86 | RARA (0.55) | CNR2S1PR1MEN1KMT2AMAPT | |
| SCHEMBL8568570 | 0.84 | RARA (0.43) | CNR2S1PR1MEN1KMT2ALMNA | |
| SCHEMBL8572694 | 0.84 | RARA (0.43) | CNR2S1PR1MEN1KMT2ALMNA | |
| SCHEMBL8574242 | 0.83 | RARA (0.47) | CNR2S1PR1MEN1KMT2ALMNA | |
| SCHEMBL8574873 | 0.83 | PPARG (0.46) | FAAHCNR2MEN1KMT2ALMNA | |
| SCHEMBL8570912 | 0.83 | PPARG (0.46) | FAAHCNR2MEN1KMT2ALMNA | |
| SCHEMBL8570423 | 0.83 | RARA (0.59) | CNR2S1PR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |
| US-5574036-A | Adamantyl-substituted polycyclic acetylene compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1996-11-12 | — | — | US | disclosed |