Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL28015424 | 0.86 | TDP1 (0.59) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL6298180 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL5156314 | 0.81 | MEN1 (0.62) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL3749117 | 0.81 | MEN1 (0.62) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL10170602 | 0.81 | MEN1 (0.62) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL2598285 | 0.79 | TDP1 (0.55) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL11214879 | 0.79 | TDP1 (0.55) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL5160730 | 0.78 | NPC1 (0.49) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL11857853 | 0.76 | MEN1 (0.57) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL8003498 | 0.76 | CA1 (0.66) | ALDH1A1MEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719139-A | BACTERICIDES | ZENECA LIMITED (GB) | 1998-02-17 | — | — | US | disclosed |
| EP-0722945-A1 | 9-oxo-1-azabicyclo(5.2.0)non-2,3-diene-2-carboxylic acid derivatives as antibiotics | ZENECA LIMITED (GB) | 1996-07-24 | — | — | EP | disclosed |