Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22303713 | 0.83 | SLC1A3 (0.48) | NPC1ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7744789 | 0.82 | SLC1A3 (0.47) | NPC1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27688813 | 0.81 | ALDH1A1 (0.51) | NPC1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5160765 | 0.81 | AKR1C3 (0.46) | NPC1ALDH1A1MEN1KMT2AMAPT | |
| Cadaverine Tartrate SCHEMBL28015424 | 0.79 | TDP1 (0.59) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL135650 | 0.79 | AKR1C3 (0.62) | NPC1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL31718130 | 0.79 | AKR1C3 (0.62) | NPC1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18924910 | 0.78 | ALDH1A1 (0.47) | NPC1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5343036 | 0.78 | ESR1 (0.64) | MAPTTDP1KDM4E | |
| SCHEMBL6298180 | 0.78 | ALDH1A1 (0.56) | NPC1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753716-A1 | BASIC SALTS AND MONOHYDRATES OF CERTAIN ALPHA, BETA-PROPRIONIC ACID DERIVATIVE | Dr. Reddy's Laboratories Ltd. (IN) | 2007-02-21 | — | — | EP | disclosed |
| WO-2006001795-A1 | BASIC SALTS AND MONOHYDRATES OF CERTAIN ALPHA, BETA-PROPRIONIC ACID DERIVATIVE | DR. REDDY'S LABORATORIES LIMITED (IN) | 2006-01-05 | — | — | WO | disclosed |
| US-20050277693-A1 | Basic salts and monohydrates of certain alpha, beta-propionic acid derivative | DR. REDDY'S LABORATORIES LIMITED | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277693-A1 | Basic salts and monohydrates of certain alpha, beta-propionic acid derivative | SRM, PKD1, CA2 | NPC1 4858/4885ALDH1A1 1421/4885MEN1 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.