Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | RAD52 | P43351 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598717 | 0.81 | RAB9A (0.47) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL2137910 | 0.80 | MAPT (0.52) | SMN1; SMN2ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL8600541 | 0.79 | KDM4E (0.51) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL8568794 | 0.77 | HPGD (0.54) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8561794 | 0.76 | VCAM1 (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8567246 | 0.75 | MAPT (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8562615 | 0.75 | KMT2A (0.51) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL21796417 | 0.75 | KDM4E (0.68) | SMN1; SMN2ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL8562721 | 0.74 | KMT2A (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5759562 | 0.73 | POLB (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |