SCHEMBL8569626

SCHEMBL8569626

CN1CCCN(c2ccc(Cl)cc2)C(Cc2ccccc2)C1

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.45
SLC6A4 P31645 4/20 0.45
SLC6A3 Q01959 3/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8567524 0.92 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL588395 0.81 DRD4 (0.56) SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL588988 0.81 DRD4 (0.56) SLC6A2SLC6A4SLC6A3ALDH1A1
Hydrochloric Acid SCHEMBL588104 0.80 DRD4 (0.55) SLC6A2SLC6A4SLC6A3ALDH1A1
Hydrochloric Acid SCHEMBL587710 0.80 DRD4 (0.55) SLC6A2SLC6A4SLC6A3ALDH1A1
Hydrochloric Acid SCHEMBL587711 0.80 DRD4 (0.55) SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL16707751 0.77
SCHEMBL8700468 0.75 ALDH1A1 (0.60) SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL588656 0.73 SLC6A4 (0.81) SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL588544 0.73 SLC6A4 (0.81) SLC6A2SLC6A4SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5716950-A NONTOXIC ANTIALLERGEN AND ANTIASTHMATIC HAVING LOW ANTIHISTAMINIC SIDE EFFECTS NIPPON SHOJI KABUSHIKI KAISHA (JP) 1998-02-10 US disclosed