SCHEMBL8567524

SCHEMBL8567524

CN1CCN(c2ccc(Cl)cc2)C(Cc2ccccc2)C1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.47
SLC6A4 P31645 4/20 0.47
SLC6A3 Q01959 3/20 0.46
ALDH1A1 P00352 1/20 0.46
DRD4 P21917 1/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
CA9 Q16790 2/20 0.42
HRH3 Q9Y5N1 1/20 0.41
DPP4 P27487 1/20 0.41
SIGMAR1 Q99720 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8569626 0.92 SLC6A2 (0.45) SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL588988 0.83 DRD4 (0.56) SLC6A2SLC6A4SLC6A3ALDH1A1DRD4
SCHEMBL588395 0.83 DRD4 (0.56) SLC6A2SLC6A4SLC6A3ALDH1A1DRD4
Hydrochloric Acid SCHEMBL588104 0.82 DRD4 (0.55) SLC6A2SLC6A4SLC6A3ALDH1A1DRD4
Hydrochloric Acid SCHEMBL587710 0.82 DRD4 (0.55) SLC6A2SLC6A4SLC6A3ALDH1A1DRD4
Hydrochloric Acid SCHEMBL587711 0.82 DRD4 (0.55) SLC6A2SLC6A4SLC6A3ALDH1A1DRD4
SCHEMBL14934671 0.80 MMP14 (0.45) SLC6A3DRD4SIGMAR1
SCHEMBL8700468 0.77 ALDH1A1 (0.60) SLC6A2SLC6A4SLC6A3ALDH1A1DRD4
SCHEMBL8918158 0.76 CA1 (0.49) CA1CA2CA4CA9DPP4
SCHEMBL2944486 0.75 SLC6A4 (0.67) SLC6A2SLC6A4SLC6A3SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5792770-A ADMINISTERING AS SEDATIVE, TRANQUILIZER, ANXIOLYTIC AGENT U C B S.A. (BE) 1998-08-11 US disclosed
US-5716950-A NONTOXIC ANTIALLERGEN AND ANTIASTHMATIC HAVING LOW ANTIHISTAMINIC SIDE EFFECTS NIPPON SHOJI KABUSHIKI KAISHA (JP) 1998-02-10 US disclosed
US-5703082-A ANTIHISTAMINE; TRANQUILIZERS U C B S.A. (BE) 1997-12-30 US disclosed