Hexane

Hexane

SCHEMBL8569764

CCCCCC.Cc1ccc2c(c1)COC21CCNCC1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.36
SIGMAR1 Q99720 1/20 0.34
SLC6A4 P31645 4/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
FASN P49327 1/20 0.32
TRPA1 O75762 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP2B6 P20813 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2A P28223 1/20 0.32
OPRM1 P35372 1/20 0.32
CYP2J2 P51589 1/20 0.32
CYP1B1 Q16678 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
TRPV3 Q8NET8 1/20 0.32
TRPV4 Q9HBA0 1/20 0.32
TRPV2 Q9Y5S1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL8569562 0.94 AVPR1A (0.37) AVPR1ASIGMAR1FASNOPRM1KDM1A
SCHEMBL3745717 0.92 AVPR1A (0.40) AVPR1ASIGMAR1FASNOPRM1KDM1A
Hydrochloric Acid SCHEMBL4985671 0.90 AVPR1A (0.39) AVPR1ASIGMAR1FASNOPRM1KDM1A
Hexane SCHEMBL8606727 0.82 SIGMAR1 (0.48) AVPR1ASIGMAR1
SCHEMBL1588901 0.81 AVPR1A (0.38) AVPR1ASIGMAR1OPRM1KDM1A
SCHEMBL4046454 0.80 SLC5A1 (0.37) SIGMAR1HTR2A
Pentane SCHEMBL8573177 0.79 SIGMAR1 (0.48) AVPR1ASIGMAR1
Hydrochloric Acid SCHEMBL4984099 0.78 SLC5A1 (0.37) SIGMAR1HTR2A
SCHEMBL16939880 0.76 AVPR1A (0.36) AVPR1A
Butane SCHEMBL8604221 0.76 SIGMAR1 (0.50) AVPR1ASIGMAR1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5837707-A USEFUL IN TREATING ANXIETY, PSYCHOSIS, EPILEPSY, CONVULSIONS, AMNESIA, PARKINSON'S DISEASE H. LUNDBECK A/S (DK) 1998-11-17 US disclosed