Butane

Butane

SCHEMBL8569562

CCCC.Cc1ccc2c(c1)COC21CCNCC1

nearest known ligand 0.55

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AVPR1A P37288 1/20 0.37
SIGMAR1 Q99720 1/20 0.35
FASN P49327 3/20 0.33
KDM1A O60341 1/20 0.33
OPRM1 P35372 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL8569764 0.94 AVPR1A (0.36) AVPR1ASIGMAR1FASNKDM1AOPRM1
SCHEMBL3745717 0.94 AVPR1A (0.40) AVPR1ASIGMAR1FASNKDM1AOPRM1
Hydrochloric Acid SCHEMBL4985671 0.93 AVPR1A (0.39) AVPR1ASIGMAR1FASNKDM1AOPRM1
SCHEMBL1588901 0.83 AVPR1A (0.38) AVPR1ASIGMAR1KDM1AOPRM1
SCHEMBL4046454 0.82 SLC5A1 (0.37) SIGMAR1
Butane SCHEMBL8604221 0.81 SIGMAR1 (0.50) AVPR1ASIGMAR1OPRM1
Hydrochloric Acid SCHEMBL4984099 0.81 SLC5A1 (0.37) SIGMAR1
SCHEMBL16939880 0.79 AVPR1A (0.36) AVPR1A
Butane SCHEMBL8575686 0.77 HTR2C (0.39) AVPR1AKDM1A
Propane SCHEMBL8890366 0.76 SIGMAR1 (0.51) AVPR1ASIGMAR1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5837707-A USEFUL IN TREATING ANXIETY, PSYCHOSIS, EPILEPSY, CONVULSIONS, AMNESIA, PARKINSON'S DISEASE H. LUNDBECK A/S (DK) 1998-11-17 US disclosed